Αρχική World News New Type of Chemotherapy Bypasses Healthy Cells to Decrease Negative Side Effects

New Type of Chemotherapy Bypasses Healthy Cells to Decrease Negative Side Effects

Chemotherapy can be a vital tool in saving a cancer patient’s life, but too often, it comes at a significant cost both financially and physically. Chemotherapy drugs work by attacking cells that are multiplying quickly. Cancer cells are among these, but so are skin cells, hair cells, blood cells, the cells in the lining of the digestive system, and a variety of other cells that help our bodies to function normally. Without these healthy cells, patients experience hair loss, decreased immune system function, dry skin, dry mouth, and other unpleasant conditions. The fact that chemotherapy isn’t capable of discriminating between healthy cells and cancer cells means many people must suffer debilitating short-term and long-term side effects from chemo drugs in the hopes that their bodies will be strong enough to handle it and that, in the end, their lives will be saved.Happily, however, a research team from the Hebrew University of Jerusalem’s Faculty of Medicine and Edmond & Lily Safra Center for Brain Sciences thinks they may have found a solution to this problem. Led by Professor Alexander Binshtok, the team has developed a way to deliver chemotherapy drugs more directly to malignant cells while bypassing healthy cells, thereby allowing patients to skip the side effects that traditionally come with chemo drugs.Photo: Adobe Stock/Viacheslav Iakobchuk
This new method may also allow doctors to give their patients reduced doses of chemotherapy drugs, because the drug will be ushered directly into each individual cancer cell and will be able to kill it more easily. This further serves to reduce side effects and improves overall prognosis and compliance among chemo patients.The new method of chemotherapy delivery works by administering a TRPV2-activator along with the chemotherapy drug to open up the TRPV2 channels of individual cancer cells. This allows the chemotherapy to get inside the cell’s cytoplasm, killing the cell more effectively. Meanwhile, channels into normal healthy cells will remain blocked off.Photo: Adobe Stock/RFBSIP“Eliminating cancerous cells while leaving healthy ones alone is an important step toward reducing patients’ suffering,” says Professor Binshtok. “It’s too early to make concrete predictions, but we are hopeful this discovery will lead the way toward a new, more targeted delivery method for chemotherapy treatment, one that will drastically reduce patients’ pain.”
Photo: Adobe Stock/felipecaparrosThe research team cautions that its new strategy will likely be difficult to implement in real healthcare situations. In the lab, they were able to inject a small amount of doxorubicin, a chemotherapeutic agent, into liver cancer cells with the degree of precision they were hoping for, but there’s still a long way to go to get this idea from the proof-of-concept stage to an actual treatment.“It’s too early to make concrete predictions but we are hopeful this discovery will lead the way towards a new, more targeted delivery method for chemotherapy treatment, one that will drastically reduce patients’ pain,” says Binshtok.We’re looking forward to seeing what this method of chemotherapy delivery evolves into in the future. This could save so many people from excessive suffering and from needing to take a break from cancer treatment because their side effects are too severe. A discovery like this will mean more lives saved and a greater quality of life for anyone undergoing chemo.
Source

NEWSLETTER

Συμπληρώστε το email σας για να λαμβάνετε τις σημαντικότερες ειδήσεις από το ogkologos.com

Βρείτε μας

2,449ΥποστηρικτέςΚάντε Like
57ΑκόλουθοιΑκολουθήστε

Διαβαστε Επίσης

Καρκίνος και Κορωνοϊός (COVID-19) ΜΕΡΟΣ Α

Εάν είστε καρκινοπαθής, το ανοσοποιητικό σας σύστημα μπορεί να μην είναι τόσο ισχυρό όσο κανονικά, έτσι μπορεί να ανησυχείτε για τους κινδύνους που σχετίζονται...

ΠΑΓΚΟΣΜΙΑ ΗΜΕΡΑ ΚΑΡΚΙΝΟΥ

Η Παγκόσμια Ημέρα Κατά του Καρκίνου καθιερώθηκε με πρωτοβουλία της Διεθνούς Ένωσης κατά του Καρκίνου (UICC), που εκπροσωπεί 800 οργανώσεις σε 155 χώρες του...

ΕΞΕΛΙΞΕΙΣ ΣΤΗ ΘΕΡΑΠΕΙΑ ΤΟΥ ΜΗ-ΜΙΚΡΟΚΥΤΤΑΡΙΚΟΥ ΚΑΡΚΙΝΟΥ ΤΟΥ ΠΝΕΥΜΟΝΑ (ΜΜΚΠ)

ΕΞΕΛΙΞΕΙΣ ΣΤΗ ΘΕΡΑΠΕΙΑ ΤΟΥ ΜΗ-ΜΙΚΡΟΚΥΤΤΑΡΙΚΟΥ ΚΑΡΚΙΝΟΥ ΤΟΥ ΠΝΕΥΜΟΝΑ (ΜΜΚΠ) Γράφει ο Δρ Παπαδούρης Σάββας, Παθόλογος-Ογκολόγος   Ο ΜΜΚΠ βρίσκεται αναλογικά στο 80% και πλέον του συνολικού...

Διατρέχουν όντως οι καρκινοπαθείς μεγαλύτερο κίνδυνο λόγω κοροναϊού;

Σε πρακτικό επίπεδο, τα δεδομένα των σχετικών μελετών υποδηλώνουν ότι η χημειοθεραπεία ή οι άλλες αντι-νεοπλασματικές θεραπείες δεν αυξάνουν σημαντικά τον κίνδυνο θνησιμότητας από...

FDA: Η ακτινοβολία των smartphones δεν προκαλεί καρκίνο

Σε μια νέα έκθεσή της, η Υπηρεσία Τροφίμων και Φαρμάκων (FDA) των ΗΠΑ αναφέρει ότι επανεξέτασε τις σχετικές επιστημονικές έρευνες που δημοσιεύθηκαν τα τελευταία...

Νέα ανακάλυψη, νέα ελπίδα για τον καρκίνο

Ένα νεοανακαλυφθέν τμήμα του ανοσοποιητικού μας συστήματος θα μπορούσε να αξιοποιηθεί για την αντιμετώπιση όλων των ειδών καρκίνου, σύμφωνα με επιστήμονες του πανεπιστημίου Cardiff...
- Advertisment -

Ροή Ειδήσεων

Combining existing drugs improves prostate cancer survival

Adding abiraterone to standard hormone therapy improves survival for men with high-risk prostate cancer that’s not spread elsewhere in the body. “Today’s results are the...

New Combination of Old Drugs Improves Survival in Patients with Prostate Cancer [ESMO Congress 2021 Press Release]

LBA4_PR - Abiraterone acetate plus prednisolone (AAP) with or without enzalutamide (ENZ) added to androgen deprivation therapy (ADT) compared to ADT alone for men...

Immunotherapy Prolongs Survival in Recurrent, Persistent or Metastatic Cervical Cancer [ESMO Congress 2021 Press Release]

LBA2_PR - Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for persistent, recurrent, or metastatic cervical cancer: Randomized, double-blind, phase 3 KEYNOTE-826 study N. Colombo1, C....

Woman Diagnosed with Breast Cancer at 33 Launches Self-Examination App

Jessica Baladad has had a long history with self-examinations after a breast cancer scare in her early 20s. This habit helped save her life,...

Extended Adjuvant Treatment with Letrozole Results in Longer Survival in Postmenopausal Patients with Breast Cancer

According to results from a prospective, open-label, phase III study conducted in 69 Italian hospitals within the Gruppo Italiano Mammella among the postmenopausal patients...

Foodie Fridays: Apple Bok Choy Salad

While the temps may still be in the 80’s, apple season is upon us! Give this Apple Bok Choy salad a try!  It is...