Αρχική World News Early Evaluation of Nutritional Status Is Needed to Provide Nutritional Support and...

Early Evaluation of Nutritional Status Is Needed to Provide Nutritional Support and Decrease Risk of Malnutrition, Sarcopenia and Nosocomial Infection in Cancer Patients

Upon hospital admission for cancer, patients already demonstrated a high prevalence of malnutrition per Global Leadership Initiative on Malnutrition (GLIM) criteria, which was associated with the risk of developing a nosocomial infection (NI) according to findings presented by Dr Martin Nuñez Abad of the Medical Oncology, Hospital General Universitario Valencia in Valencia, Spain at the ESMO Virtual Congress 2020.

Dr Nuñez Abad and colleagues investigated the nutritional status in patients hospitalised for cancer to determine the prevalence of malnutrition according to GLIM criteria, and to determine the association between malnutrition and the risk of NI and length of hospital stay.

This prospective observational study was carried out in patients admitted to the Oncology Department of the General University Hospital of Valencia from November 2019 to March 2020. Nutritional status was evaluated within the first 48 hours after admission. The body mass criteria used included the fat free mass index (FFMI) and phase angle (PA), as measured using a bioelectrical impedance (Akern®). Muscle function was evaluated using a Jamar® handgrip. The extent of sarcopenia was measured using the cut-off values established by the European Working Group on Sarcopenia in Older People 2 (EWGSOP2).

At admission, nearly half of the patients had malnutrition

This study included 107 patients with a mean age of 66 years; 66.4% of patients were male, and most (70.1%) patients had advanced disease.

The investigators found that, on admission, 48 (44.9%) patients presented with severe and 19 (17.8%) patients had moderate malnutrition per GLIM criteria. In addition, 77 (72%) patients also presented with dynapenia and 18 (16.8%) patients had sarcopenia.

Regarding other parameters of nutritional status, the mean weight was 67.8 kg, mean BMI was 24 kg/m2, mean FFMI and 18.6 kg/m2 and mean PA was 4.5º in these patients overall.

During a mean hospital stay of 13.9 days, 43 (40.2%) patients developed a NI, which were primarily respiratory tract infections in 26 patients. Patients developing a NI had significantly lower weight, BMI and FFMI than the overall patient cohort (p < 0.05 all comparisons), but PA was not lower.

Early-Evaluation-of-Nutritional-Status-Is-Needed-1810O-Image1

Association of weight, body mass index, fat free mass index and phase angle with nosocomial infections in cancer patients admitted to hospital.

© Martin Nuñez Abad.

The proportion of infections rose as the nutritional status worsened

NI occurred in 8 of 19 (42.1%) patients with moderate malnutrition and 25 of 48 (52.1%) patients with severe malnutrition compared with 10 infections in 40 (25%) patients without signs of malnutrition (p = 0.035). The incidence of NI was highest in patients with sarcopenia (61.1%), as compared with 36% in the hospitalised patients overall (p = 0.044).

Early-Evaluation-of-Nutritional-Status-Is-Needed-1810O-Image2

Proportion of nosocomial infections in cancer inpatients according to nutritional status and sarcopenia.

© Martin Nuñez Abad.

The length of hospital stay was prolonged in patients with NI compared to patients overall; the mean length of stay was 18.6 versus 10.8 days (p < 0,024).

Length of hospital stay was not found to be related to nutritional status.

Conclusions

According to the authors, the prevalence of malnutrition in patients hospitalised for cancer is high. Malnutrition per GLIM criteria and sarcopenia are associated with a high risk of NI.

The investigators advise that an adequate nutritional evaluation is essential for timely implementation of nutritional support, to avoid malnutrition, sarcopenia and to decrease NI.

No external funding was reported for this study.

Reference

1810O – Nuñez Abad M, Garrido Gallego J, Iranzo V, et al. Impact of malnutrition according to the GLIM criteria in cancer patients admitted to hospital. ESMO Virtual Congress 2020.

Source

NEWSLETTER

Συμπληρώστε το email σας για να λαμβάνετε τις σημαντικότερες ειδήσεις από το ogkologos.com

Βρείτε μας

2,449ΥποστηρικτέςΚάντε Like
57ΑκόλουθοιΑκολουθήστε

Διαβαστε Επίσης

ΕΞΕΛΙΞΕΙΣ ΣΤΗ ΘΕΡΑΠΕΙΑ ΤΟΥ ΜΗ-ΜΙΚΡΟΚΥΤΤΑΡΙΚΟΥ ΚΑΡΚΙΝΟΥ ΤΟΥ ΠΝΕΥΜΟΝΑ (ΜΜΚΠ)

ΕΞΕΛΙΞΕΙΣ ΣΤΗ ΘΕΡΑΠΕΙΑ ΤΟΥ ΜΗ-ΜΙΚΡΟΚΥΤΤΑΡΙΚΟΥ ΚΑΡΚΙΝΟΥ ΤΟΥ ΠΝΕΥΜΟΝΑ (ΜΜΚΠ) Γράφει ο Δρ Παπαδούρης Σάββας, Παθόλογος-Ογκολόγος   Ο ΜΜΚΠ βρίσκεται αναλογικά στο 80% και πλέον του συνολικού...

Διατρέχουν όντως οι καρκινοπαθείς μεγαλύτερο κίνδυνο λόγω κοροναϊού;

Σε πρακτικό επίπεδο, τα δεδομένα των σχετικών μελετών υποδηλώνουν ότι η χημειοθεραπεία ή οι άλλες αντι-νεοπλασματικές θεραπείες δεν αυξάνουν σημαντικά τον κίνδυνο θνησιμότητας από...

FDA: Η ακτινοβολία των smartphones δεν προκαλεί καρκίνο

Σε μια νέα έκθεσή της, η Υπηρεσία Τροφίμων και Φαρμάκων (FDA) των ΗΠΑ αναφέρει ότι επανεξέτασε τις σχετικές επιστημονικές έρευνες που δημοσιεύθηκαν τα τελευταία...

Νέα ανακάλυψη, νέα ελπίδα για τον καρκίνο

Ένα νεοανακαλυφθέν τμήμα του ανοσοποιητικού μας συστήματος θα μπορούσε να αξιοποιηθεί για την αντιμετώπιση όλων των ειδών καρκίνου, σύμφωνα με επιστήμονες του πανεπιστημίου Cardiff...

Καρκίνος: Ευεργετική για τους καρκινοπαθείς η άσκηση

Σημαντικά ωφέλη προσφέρει η άσκηση, ακόμη και σε ασθενείς με καρκίνο. Οι περισσότεροι ασθενείς αγνοούν τα οφέλη που μπορεί να έχει γι’ αυτούς η συχνή...

Prostate Cancer

The article is provided by Scientific Communications Officer of NIPD Genetics, Ms Marina Charitou (MSc) Prostate Cancer Awareness Prostate cancer is the second most common cancer...
- Advertisment -

Ροή Ειδήσεων

Feasibility and Preliminary Efficacy Results of the Beat AML Study

Precision medicine in acute myeloid leukaemia (AML) is feasible in terms of providing cytogenetic and mutational data within 7 days, allowing their rapid incorporation into...

Woman Battles Breast Cancer While Pregnant, Delivers Healthy Baby Boy

When she was six months pregnant, Desiree Doughty noticed that something seemed to be wrong with her breasts. “I noticed that one of my breasts...

Pumpkin Season!

Halloween may look different this year but we can still decorate our homes and enjoy a favorite fall treat – pumpkin and pumpkin seeds....

ACHIEVE-2 Results of Oxaliplatin-Based Adjuvant Chemotherapy in Asian Patients with High-Risk Stage II Colon Cancer

The Asian researchers reported on 25 October 2020 in the Annals of Oncology that 3-month of combination therapy for adjuvant treatment of high-risk stage...

GreaterGood’s Mask Donations Are Helping LA Family Housing Keep Homeless People Safe

Due to the COVID-19 pandemic, people everywhere are uncertain about the future of their health, safety, and economic security. Homeless people and those who...

How I Found a Meaningful Career After Cancer

Jacky Costello is the founder and owner of a house cleaning company serving the greater Tampa Bay area in Florida. Through her company's partnership with...