{"id":27327,"date":"2021-08-05T14:00:00","date_gmt":"2021-08-05T14:00:00","guid":{"rendered":"https:\/\/ogkologos.com\/2021-asco-annual-meeting-research-round-up-advances-in-treating-lung-cancer-breast-cancer-and-sarcoma\/"},"modified":"2024-11-03T15:14:33","modified_gmt":"2024-11-03T15:14:33","slug":"2021-asco-annual-meeting-research-round-up-advances-in-treating-lung-cancer-breast-cancer-and-sarcoma","status":"publish","type":"post","link":"https:\/\/ogkologos.com\/en\/2021-asco-annual-meeting-research-round-up-advances-in-treating-lung-cancer-breast-cancer-and-sarcoma\/","title":{"rendered":"2021 ASCO Annual Meeting Research Round Up: Advances in Treating Lung Cancer, Breast Cancer, and Sarcoma"},"content":{"rendered":"<p>In the annual Research Round Up series, Cancer.Net Associate Editors answer the question, <em>\u201cWhat was the most exciting or practice-changing research in your field presented at the 2021 ASCO Annual Meeting?\u201d<\/em> In this episode, 3 experts discuss new research from the meeting in lung cancer, breast cancer, and sarcoma.<\/p>\n<p>Listen below, and <a href=\"https:\/\/www.cancer.net\/blog\/podcasts\">subscribe to Cancer.Net Podcasts<\/a> wherever you listen to podcasts&nbsp;for new episodes in this series throughout the summer.<\/p>\n<h3>Research on new treatments for non-small cell lung cancer<\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.cancer.net\/sites\/cancer.net\/files\/rru-aggarwal.png\" alt=\"Dr. Charu Aggarwal\" width=\"100\" height=\"150\">Dr. Charu Aggarwal, the 2021 <a href=\"https:\/\/www.cancer.net\/node\/41705\">Cancer.Net Associate Editor for Lung Cancer<\/a>, discusses results from 3 studies evaluating new treatments for <a href=\"https:\/\/www.cancer.net\/node\/31273\">non-small cell lung cancer<\/a> (NSCLC). First, she discusses the <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03600883\" target=\"_blank\" rel=\"noopener\">phase 2 CodeBreaK 100 clinical trial<\/a>, which evaluated whether using the targeted therapy sotorasib (Lumakras) to treat people with metastatic non-small cell lung cancer with a <em>KRAS G12C<\/em> mutation shrank the tumors. [2:35] Next, she discusses a 5-year update from the <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02125461\" target=\"_blank\" rel=\"noopener\">phase 3 PACIFIC clinical trial<\/a> on whether treating people with stage III (3) non-small cell lung cancer using the immunotherapy durvalumab (Imfinzi) following chemotherapy with radiation therapy helped them live longer. [4:46] Finally, she discusses the <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02486718\" target=\"_blank\" rel=\"noopener\">phase 3 Impower010 clinical trial<\/a>, which tested whether treating people with early-stage non-small cell lung cancer with the immunotherapy atezolizumab (Tecentriq) following surgery and chemotherapy reduced their risk of recurrence, or the cancer coming back. [6:46]<\/p>\n<h3>Advances in treating early-stage breast cancer<\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.cancer.net\/sites\/cancer.net\/files\/rru-henry.jpg\" alt=\"Dr. Lynn Henry\" width=\"100\" height=\"150\">Dr. Lynn Henry, the 2021 <a href=\"https:\/\/www.cancer.net\/node\/38261\">Cancer.Net Associate Editor for Breast Cancer<\/a>, discusses results from 2 studies in <a href=\"https:\/\/www.cancer.net\/node\/31322\">breast cancer<\/a>, the first of which was the <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02032823\" target=\"_blank\" rel=\"noopener\">phase 3 OlympiA clinical trial<\/a>. In this study, researchers were evaluating whether treating people with a&nbsp;<em>BRCA<\/em>&nbsp;mutation and early-stage, HER2-negative breast cancer using olaparib (Lynparza), a type of targeted therapy called a PARP inhibitor, decreased the likelihood of the cancer returning. [10:40] Dr. Henry also discusses the final results from the <a href=\"https:\/\/ascopubs.org\/doi\/abs\/10.1200\/JCO.2021.39.15_suppl.516\" target=\"_blank\" rel=\"noopener\">phase 3 PROMISE-GIM6 clinical trial<\/a>. Sometimes, ovarian suppression is given to preserve a patient\u2019s ability to have children, or fertility, after treatment with chemotherapy ends. This trial was observing whether ovarian suppression combined with chemotherapy impacted a patient\u2019s risk of recurrence. [12:47]<\/p>\n<h3>Research highlights for the treatment of sarcoma<\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.cancer.net\/sites\/cancer.net\/files\/vicki-keedy.jpg\" alt=\"Dr. Vicki Keedy\" width=\"100\" height=\"150\">Dr. Vicki Keedy, the 2021 <a href=\"https:\/\/www.cancer.net\/node\/38241\">Cancer.Net Associate Editor for Sarcoma<\/a>, discusses results from 2 studies testing new treatments for <a href=\"https:\/\/www.cancer.net\/node\/31379\">sarcoma<\/a>. The first study, the <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04044768\" target=\"_blank\" rel=\"noopener\">phase 2 SPEARHEAD-1 clinical trial<\/a>, looked at whether treating people with metastatic synovial sarcoma or myxoid\/round cell liposarcoma using afami-cel, a type of immunotherapy called T-cell receptor therapy, shrank the tumors. [15:38] The second study evaluated whether treating people with metastatic synovial sarcoma using catequentinib, a type of targeted therapy called a tyrosine kinase inhibitor, slowed down their tumor growth compared to treatment with the chemotherapy dacarbazine (DTIC). [18:42]<\/p>\n<p>Disclosure information for this podcast\u2019s speakers can be found in their individual biographies, which are linked to in the paragraphs above.<\/p>\n<p><strong><em>Was this podcast useful?<\/em><\/strong> <em>Please subscribe, rate, and review Cancer.Net Podcasts wherever you listen to podcasts. This prerecorded podcast can be listened to online or downloaded to your computer. A <a href=\"https:\/\/www.cancer.net\/node\/41754\">transcript<\/a> is also available. For more information, visit the<\/em> <a href=\"http:\/\/www.cancer.net\/blog\/podcasts\"><em>Cancer.Net podcast page<\/em><\/a><em><span>.<\/span><\/em><\/p>\n<p><em>Cancer.Net podcasts are edited for length and content.<\/em><\/p>\n<p><a href=\"https:\/\/www.cancer.net\/blog\/2021-08\/2021-asco-annual-meeting-research-round-advances-treating-lung-cancer-breast-cancer-and-sarcoma\">Source<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In the annual Research Round Up series, Cancer.Net Associate Editors answer the question, \u201cWhat was the most exciting or practice-changing research in your field presented at the 2021 ASCO Annual Meeting?\u201d In this episode, 3 experts discuss new research from the meeting in lung cancer, breast cancer, and sarcoma. Listen below, and subscribe to Cancer.Net [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[5137],"tags":[],"class_list":["post-27327","post","type-post","status-publish","format-standard","hentry","category-world-news"],"_links":{"self":[{"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/posts\/27327","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/comments?post=27327"}],"version-history":[{"count":1,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/posts\/27327\/revisions"}],"predecessor-version":[{"id":43675,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/posts\/27327\/revisions\/43675"}],"wp:attachment":[{"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/media?parent=27327"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/categories?post=27327"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/tags?post=27327"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}