{"id":26993,"date":"2021-04-26T10:42:18","date_gmt":"2021-04-26T10:42:18","guid":{"rendered":"https:\/\/scienceblog.cancerresearchuk.org\/?p=18455"},"modified":"2024-11-03T15:14:57","modified_gmt":"2024-11-03T15:14:57","slug":"e-cigarettes-what-we-know-and-what-we-dont","status":"publish","type":"post","link":"https:\/\/ogkologos.com\/en\/e-cigarettes-what-we-know-and-what-we-dont\/","title":{"rendered":"E-cigarettes: what we know and what we don\u2019t"},"content":{"rendered":"<div class=\"image hero-image\"><img decoding=\"async\" width=\"620\" height=\"348\" src=\"https:\/\/zniup3zx6m0ydqfpv9y6sgtf-wpengine.netdna-ssl.com\/wp-content\/uploads\/2021\/04\/shutterstock_vaping_e-cigarette.jpg\" class=\"attachment-featuredImage size-featuredImage\" alt=\"A man vaping\" loading=\"lazy\" srcset=\"https:\/\/zniup3zx6m0ydqfpv9y6sgtf-wpengine.netdna-ssl.com\/wp-content\/uploads\/2021\/04\/shutterstock_vaping_e-cigarette.jpg 620w, https:\/\/zniup3zx6m0ydqfpv9y6sgtf-wpengine.netdna-ssl.com\/wp-content\/uploads\/2021\/04\/shutterstock_vaping_e-cigarette-300x168.jpg 300w, https:\/\/zniup3zx6m0ydqfpv9y6sgtf-wpengine.netdna-ssl.com\/wp-content\/uploads\/2021\/04\/shutterstock_vaping_e-cigarette-220x123.jpg 220w, https:\/\/zniup3zx6m0ydqfpv9y6sgtf-wpengine.netdna-ssl.com\/wp-content\/uploads\/2021\/04\/shutterstock_vaping_e-cigarette-150x84.jpg 150w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" data-attachment-id=\"18456\" data-permalink=\"https:\/\/scienceblog.cancerresearchuk.org\/2021\/04\/26\/e-cigarettes-what-we-know-and-what-we-dont\/shutterstock_vaping_e-cigarette\/\" data-orig-file=\"https:\/\/scienceblog.cancerresearchuk.org\/wp-content\/uploads\/2021\/04\/shutterstock_vaping_e-cigarette.jpg\" data-orig-size=\"620,348\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;Copyright (c) 2019 Shutterstock. No use without permission.&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"shutterstock_vaping_e-cigarette\" data-image-description data-medium-file=\"https:\/\/scienceblog.cancerresearchuk.org\/wp-content\/uploads\/2021\/04\/shutterstock_vaping_e-cigarette-300x168.jpg\" data-large-file=\"https:\/\/scienceblog.cancerresearchuk.org\/wp-content\/uploads\/2021\/04\/shutterstock_vaping_e-cigarette.jpg\"><\/div>\n<p>It\u2019s been a decade since e-cigarettes first gained popularity in the UK. Since then, the types of devices available and the number of people using them has risen sharply.<\/p>\n<p>And as the popularity levels of e-cigarettes grew, so did the debate around them.<\/p>\n<p>The big selling point for e-cigarettes is they\u2019re a way to help people stop smoking and reduce harm from the biggest cause of cancer in the world, tobacco.<\/p>\n<p>But it\u2019s a balancing act. E-cigarettes contain nicotine and so it\u2019s important to make sure that people who have never smoked, particularly young people, don\u2019t start to use them.<\/p>\n<p>While it may be hard to remember a time before vaping, in the grand scheme of research, 10 years isn\u2019t that long. And there\u2019s still a lot more we need to understand about them.<\/p>\n<p>Linda Bauld, Professor of Public Health at the University of Edinburgh and Cancer Research UK\u2019s prevention adviser says, \u201cThese are still relatively new products. But a huge amount of research has been done. It\u2019s a far more sophisticated discussion now than it was in the early years.\u201d<\/p>\n<p>Here are the big questions around e-cigarettes, what we know and what we still need to find out.<\/p>\n<h2>Is vaping safe?<\/h2>\n<p>Around 12,000 of us Google this each month in the UK. And you can understand why \u2013 there are a lot of mixed messages out there when it comes to e-cigarettes, with many headlines proclaiming that vaping is just as bad or worse than smoking.<\/p>\n<p>In fact, <strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25108741\/\">research<\/a> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3691171\/?tool=pmcentrez&amp;report=abstract\">shows<\/a> that vaping is far less harmful than smoking<\/strong>.<\/p>\n<div class=\"info-box-full-width-no-bg\" readability=\"8\">\n<h3>What are e-cigarettes\/vapes?<\/h3>\n<p>E-cigarettes (also known as vapes) heat a liquid so that it becomes vapour and people can breathe it in. They usually contain nicotine which is the addictive chemical found in cigarettes.<\/p>\n<\/div>\n<p>Some studies have shown harmful effects of e-cigarette vapour. However, these are usually conducted on animals or cells in the lab, rather than in people. And the concentrations of e-cigarette vapour used are often much higher than people would be exposed to in real life.<\/p>\n<p>Whilst these studies are useful to explore the potential effects of e-cigarettes, they shouldn\u2019t be used to estimate real-world impact in humans.<\/p>\n<p>The tone of the debate may also depend on where you live. In 2019, the US saw an outbreak of several thousand cases of respiratory illness and nearly 70 deaths linked to the use of vaping products. But again, headlines can be misleading, as these cases were due to contaminants in illegal products and not linked to regular vaping. There was no similar outbreak in the UK, and the chemicals of concern are banned.<\/p>\n<p>The <a href=\"https:\/\/assets.publishing.service.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/684963\/Evidence_review_of_e-cigarettes_and_heated_tobacco_products_2018.pdf\">best evidence available<\/a> in humans shows <a href=\"https:\/\/www.rcplondon.ac.uk\/projects\/outputs\/nicotine-without-smoke-tobacco-harm-reduction\">e-cigarettes are far less harmful than smoking.<\/a> For example, one study found significantly lower levels of exposure to harmful chemicals in people who switch from smoking to vaping compared with those who continued to smoke. These levels were similar to people using nicotine replacement therapy (NRT). There\u2019s also no good evidence that second-hand e-cigarette vapour is harmful to bystanders.<\/p>\n<p>But e-cigarettes are a relatively new product. For this reason, there isn\u2019t enough research into long-term use, or into their effects in people who have never smoked.<\/p>\n<p>\u201cIn people who vape, the vast majority are smokers or ex-smokers. So unpicking the relationship between those two risks is really tough\u201d says Bauld. \u201cDefinitive answers about safety may still take many years to identify\u201d.<\/p>\n<p>In short, there\u2019s a lot more to learn.<\/p>\n<p>But what researchers have had time to observe, over decades, is the huge amounts of research showing that tobacco is extremely harmful. Which is why experts can be confident that e-cigarettes are far less harmful than tobacco. This is broadly agreed by researchers and public health bodies.<\/p>\n<h2>Do e-cigarettes help people to stop smoking?<\/h2>\n<p>There\u2019s <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27622384\/\">growing evidence<\/a> from around the world that e-cigarettes can help people stop smoking. In England, a study that looked at e-cigarette use and smoking cessation across the population estimated that <a href=\"https:\/\/www.bmj.com\/content\/354\/bmj.i4645\">e-cigarettes helped an additional 18,000 people<\/a> in England in 2015 to quit for the long term.<\/p>\n<p><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1808779\">Research shows<\/a> the best way to stop smoking is through stop smoking services using a combination of counselling and prescription medication. We now have evidence that e-cigarettes combined with the behavioural support from stop smoking services are also effective in helping people to stop smoking.<\/p>\n<p>Bauld says that smoking is still the largest preventable cause of cancer and is linked to 15 different types. \u201cSupporting smokers to quit and young people to not start is a really important cancer prevention priority. So, if e-cigarettes can provide support for individuals as an aid to smoking cessation, then that\u2019s of interest to cancer researchers.\u201d<\/p>\n<p>But there\u2019s still a lot we need to find out. For example, there\u2019s limited research into the role that different types of devices, nicotine concentrations and flavours play in helping people to stop smoking.<\/p>\n<p>Although smoking rates in the UK continue to fall, <a href=\"https:\/\/www.cancerresearchuk.org\/health-professional\/our-reports-and-publications#info-gallery-id-5_slide-2\">levels in the most deprived populations<\/a> are still much higher than in the least deprived, so experts are especially interested in whether e-cigarettes could help reduce this inequality. <a href=\"https:\/\/bmcpublichealth.biomedcentral.com\/articles\/10.1186\/s12889-020-8270-3\">Recent research<\/a> has suggested that people from lower socioeconomic groups might be more likely to use e-cigarettes, but it\u2019s not yet clear whether this means e-cigarettes are improving smoking cessation rates in these communities.<\/p>\n<h2>Does vaping in young people lead to smoking?<\/h2>\n<p>Another question which often makes the headlines is around youth vaping and whether e-cigarettes are causing people to start smoking \u2013 the so-called \u2018gateway effect\u2019.<\/p>\n<p>Overall, there\u2019s no strong evidence for a gateway effect in the UK. Although experimentation with e-cigarettes among young people has increased in recent years, regular vaping in young people in the UK remains very low. In a <a href=\"https:\/\/ash.org.uk\/information-and-resources\/fact-sheets\/statistical\/use-of-e-cigarettes-among-young-people-in-great-britain-2020\/\">representative survey<\/a> of 11 to 18 year-olds in Great Britain in 2020, out of 1,926 never smokers, not a single person reported vaping daily.<\/p>\n<p><a href=\"https:\/\/tobaccocontrol.bmj.com\/content\/30\/2\/212\">Some research<\/a> <a href=\"https:\/\/tobaccocontrol.bmj.com\/content\/30\/1\/8\">shows<\/a> that young people who use e-cigarettes are more likely to smoke later on. But it\u2019s a tricky relationship to untangle, as young people who smoke are more likely to vape. Experts have suggested that some young people are generally more likely to engage in \u2018risky\u2019 behaviours \u2013 like alcohol, drug use or smoking and vaping. Therefore, studies examining smoking and vaping in young people don\u2019t necessarily show that vaping leads them to start smoking, but that they may be likely to do both anyway.<\/p>\n<p>And the good news is that smoking rates and the perceptions around the acceptability of smoking have declined in young people, even since the introduction of e-cigarettes. So, it doesn\u2019t seem like e-cigarettes have interfered with the promising drop in levels of smoking in young people.<\/p>\n<p>Currently, the evidence doesn\u2019t suggest that young people who have never smoked are vaping regularly, or that vaping is causing more young people in the UK to start smoking. But, vaping in young people is something we\u2019re keeping an eye on.<\/p>\n<h2>Is it OK to smoke and vape at the same time?<\/h2>\n<p>There\u2019s currently <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28166548\/\">no evidence<\/a> that using both cigarettes and e-cigarettes is worse than just smoking. But it\u2019s clear that to get the health benefits, people need to switch completely from smoking to vaping.<\/p>\n<p>And there are still unanswered questions here. It may be that some people go through a period where they both smoke and vape to help them quit, but right now we don\u2019t know how long this transition period is, or how it varies from person to person.<\/p>\n<p>Experts need to find out what causes people to switch from vaping and smoking to just vaping and how they can support people to do this.<\/p>\n<h2>Getting answers<\/h2>\n<p>Highlighting some of the main gaps in the current research, Bauld says that we don\u2019t know enough about how people use e-cigarettes over time \u2013 including how use patterns change and if and when people stop using them. \u201cWe have some studies, but they\u2019re really quite limited. We also don\u2019t know enough about the impact of long-term use of these devices on health.\u201d<\/p>\n<p>At Cancer Research UK, we fund lots of research into the role of e-cigarettes in smoking cessation and their use in young people, which compliments research across the world to answer these big questions. And we work with policy makers to ensure that regulations match the rapidly evolving research in the area and engage with the public to ensure they receive accurate information.<\/p>\n<p>In 2020, we took it one step further, uniting with the US National Cancer Institute to launch Cancer Grand Challenges \u2013 a global funding platform that supports world-class teams of researchers to take on <a href=\"https:\/\/scienceblog.cancerresearchuk.org\/2020\/10\/14\/were-asking-scientists-to-tackle-9-of-the-toughest-challenges-in-cancer-research\/\">some of the toughest challenges in cancer research<\/a>. This includes a challenge focused on e-cigarettes, inviting the global research community to answer the big questions surrounding their use.<\/p>\n<p>Large, long-term studies examining topics such as harms, youth use, use patterns over time, use of flavours and effectiveness in smoking cessation are needed.<\/p>\n<p>And to get the answers we need about the effects of different regulations, these studies need to be conducted across the world. This will allow governments and health bodies to develop laws that protect young people from vaping, but also allow e-cigarettes to continue to be used to help people stop smoking.<\/p>\n<p>There\u2019s a lot we still need to know, but the evidence has come a long way so far. And all this evidence is why at Cancer Research UK, we recommend people who smoke consider using e-cigarettes as an option to help them quit, but why we would discourage people who have never smoked from starting to vape.<\/p>\n<div class=\"info-box-full-width-no-bg\" readability=\"8.112676056338\">\n<p><strong>For up to date, accurate information on e-cigarettes, visit our<\/strong> <a href=\"https:\/\/www.cancerresearchuk.org\/about-cancer\/causes-of-cancer\/smoking-and-cancer\/is-vaping-harmful\"><strong>webpage<\/strong><\/a><\/p>\n<\/div>\n<p><em>Alice Davies is a health information officer at Cancer Research UK<\/em><\/p>\n<p><h3 class=\"panel-title\">More on this topic<\/h3>\n<\/p>\n<p> <a href=\"http:\/\/feedproxy.google.com\/~r\/cancerresearchuk\/SHhE\/~3\/q_qnbUJZIKM\/\">Source<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>It\u2019s been a decade since e-cigarettes first gained popularity in the UK. Since then, the types of devices available and the number of people using them has risen sharply. And as the popularity levels of e-cigarettes grew, so did the debate around them. The big selling point for e-cigarettes is they\u2019re a way to help [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[5137],"tags":[],"class_list":["post-26993","post","type-post","status-publish","format-standard","hentry","category-world-news"],"_links":{"self":[{"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/posts\/26993","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/comments?post=26993"}],"version-history":[{"count":1,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/posts\/26993\/revisions"}],"predecessor-version":[{"id":45340,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/posts\/26993\/revisions\/45340"}],"wp:attachment":[{"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/media?parent=26993"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/categories?post=26993"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/tags?post=26993"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}