{"id":26078,"date":"2020-06-20T07:30:04","date_gmt":"2020-06-20T07:30:04","guid":{"rendered":"https:\/\/scienceblog.cancerresearchuk.org\/?p=17698"},"modified":"2024-11-03T15:16:46","modified_gmt":"2024-11-03T15:16:46","slug":"news-digest-targeted-lava-lamp-treatment-skin-cancer-biopsies-and-the-iknife","status":"publish","type":"post","link":"https:\/\/ogkologos.com\/en\/news-digest-targeted-lava-lamp-treatment-skin-cancer-biopsies-and-the-iknife\/","title":{"rendered":"News digest \u2013 targeted \u2018lava lamp\u2019 treatment, skin cancer biopsies and the iKnife"},"content":{"rendered":"
<\/p>\n

Credit: John Marshall, Tumour Biology Lab & EM Unit<\/span><\/p>\n<\/div>\n

With news about the coronavirus pandemic developing daily, we want to make sure everyone affected by cancer gets the information they need during this time.<\/span><\/em> <\/span><\/p>\n

We\u2019re pulling together the latest government and NHS health updates from across the UK in a separate blog post<\/a>, which we\u2019re updating regularly.<\/span><\/em> <\/span><\/p>\n

\u2018Lavalamp\u2019 effect could make cancer drugs more powerful<\/h2>\n

A new study published in<\/span> Science<\/span><\/em> has<\/span> revealed how<\/span> drug molecules<\/span> are organised when they<\/span> enter a cell<\/span>,<\/span> and how<\/span> this information could<\/span> be used to make certain drugs hit their targets more effectively. Research found that cancer drug compounds become concentrated in certain spots within cells \u2013 like blobs in a<\/span> lava lamp<\/span>.<\/span> Whilst<\/span> s<\/span>cientists<\/span> hope that a better understanding of this phenomenon could lead to more targeted cancer treatments,<\/span> others think that<\/span> other mechanisms should be<\/span> explored<\/span>.<\/span> Find out more at<\/span> Nature<\/a>. <\/span> <\/span><\/p>\n

Swansea skin cancer patients receive pioneering procedure<\/h2>\n

Skin cancer patients in Swansea have become first in the world to receive complex biopsies while awake. Sentinel lymph node biopsies allow doctors to detect whether melanoma has spread in skin cancer patients, but the procedure was suspended due to Covid-19 restrictions on general anaesthetic. A team of plastic surgeons and anaesthetists at Sancta Maria Hospital are now the first to carry out the procedure without anaesthetic. So far nine patients have had the test. More on this at<\/span> BBC<\/a>.<\/span><\/p>\n

Scientist uncover new mechanism driving colorectal cancer<\/h2>\n

MedicalXpress<\/span><\/a> reports on a collaborative study that has revealed a new mechanism causing colorectal cancer. Research by VIB-<\/span>UGent<\/span> Center<\/span> for Inflammation Research and Ghent University found that abnormal expression of the protein Zeb2 could allow harmful bacteria into the intestinal wall, causing inflammation and driving cancer progression. Scientists have now demonstrated how manipulating the<\/span> immune<\/span> system <\/span>could prevent this development and potentially lead to new cancer treatments. <\/span> <\/span><\/p>\n

Searching for novel connections in cancer metabolism<\/h2>\n

Dr George<\/span> Poulogiannis<\/span> is<\/span> one of our scientists investigating the relationship between cellular metabolism, cancer and diet<\/span>. In our blog post<\/a>, we spoke to him<\/span> about how his team have been<\/span> investigating<\/span> connections in metabo<\/span>lism<\/span> by utilising<\/span> a unique tool<\/span> known as the<\/span> iKnife<\/span>,<\/span> used in cancer surgery<\/span>,<\/span> in order to<\/span> open the door to a better understanding of individual cancers<\/span>.<\/span> Whilst the team<\/span> have uncovered new features of breast cancer biology linked to metabolism<\/span> and<\/span> diet<\/span>,<\/span> and<\/span> have shown that a dietary fat restriction plays a major role in therapy response,<\/span> so<\/span>me<\/span> headlines<\/a> were quick to jump to a \u2018potential cancer cure<\/span>\u2019<\/span>.<\/span> <\/span> <\/span><\/p>\n

And<\/span><\/strong> finally<\/span><\/strong>\u2026<\/span><\/strong> <\/span><\/h2>\n

A technique known as a liquid biopsy is allowing doctors to find out more about a patient\u2019s cancer without the need for surgery. The technique analys<\/span>es<\/span> a patient\u2019s blood, monitoring the DNA tumours release into the blood stream. By analysing the individual genetic makeup of a tumour, liquid biopsies can<\/span> focus<\/span> on a specific set of mutations and use them as a starting point to monitor the progression of cancer. Find the full story on<\/span> our blog<\/a>.<\/span> <\/span><\/p>\n

Scarlett Sangster is a writer for PA Media Group<\/em><\/p>\n

More on this topic<\/h3>\n<\/p>\n

Source<\/a><\/p>","protected":false},"excerpt":{"rendered":"

Credit: John Marshall, Tumour Biology Lab & EM Unit With news about the coronavirus pandemic developing daily, we want to make sure everyone affected by cancer gets the information they need during this time.  We\u2019re pulling together the latest government and NHS health updates from across the UK in a separate blog post, which we\u2019re […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[5137],"tags":[],"class_list":["post-26078","post","type-post","status-publish","format-standard","hentry","category-world-news"],"_links":{"self":[{"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/posts\/26078","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/comments?post=26078"}],"version-history":[{"count":1,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/posts\/26078\/revisions"}],"predecessor-version":[{"id":44270,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/posts\/26078\/revisions\/44270"}],"wp:attachment":[{"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/media?parent=26078"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/categories?post=26078"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ogkologos.com\/en\/wp-json\/wp\/v2\/tags?post=26078"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}